Job Title
Professor of Clinical Orthopaedics
Institution
University College London
Research Area (broad)
Surgical
Research Area (specific)
RCS Research Fellowship
Overarching Research Aim

Alister Hart’s surgical and research interests focus on the achievement of the best possible patient and clinical outcomes after hip replacement, through implant design, surgical positioning and patient factors.

Current Rosetrees Research Project Detail

We will create state-of-the-art, true-to-life training for surgeons to practice hip replacement surgery.


Hip replacement is a common treatment for arthritic hip joints (80,000 per annum in the UK) and revision hip replacement has doubled in the last 5 years (10,000 per annum in the UK in 2012). With increasing population and life expectancy, the number of  hip replacement operations (both primary and revision surgery) is predicted to increase. Primary hip replacement operations will almost triple by 2030.  It is known that surgical training using a surgical simulation method can improve patients outcome after primary and revision hip replacement and reduce the number of redo / revision hip replacements. However, the delivery of surgical simulation can be costly and time consuming. Clinically relevant and cost-effective learning in the area of hip replacement is needed and would have an impact on a large number of patients and the NHS.  We aim to create innovative, practical and cost-effective training for surgeons to improve the clinical outcome for patients undergoing hip surgery.  Beyond this study courses will be run at multiple sites for speedy and more effective dissemination and to maximise the number of surgeons and patients to be benefited from the technology.

Summary of Researcher Background

Alister Hart is head of clinical research in orthopaedics at UCL and the director of research and development at the Royal National Orthopaedic Hospital (RNOH). He studied medicine at Caius College Cambridge (q 1994), did basic surgical training at Guy’s and St Thomas’ Hospitals and higher surgical training on the RNOH rotation. In 2006 he was appointed Clinical Senior Lecturer and Consultant Orthopaedic Surgeon at Imperial College London and in 2012 to the present position.


His research interest on the performance of orthopaedic implants is complemented by his clinical practice as a hip and knee implant surgeon: he has performed more than 3000 operations including 900 revision hip and knee replacements.


He is a co-director, with John Skinner, of the London Implant Retrieval Centre. He teaches on aspects of hip surgery to surgeons of all grades, including orthopaedic basic sciences, patient assessment using clinical examination and imaging, patient management and surgical technique.

Outcomes

  1. Siddiqui IA, Sabah SA, Satchithananda K, Lim AK, Cro S, Henckel J, Skinner JA, Hart AJ.(2014) A comparison of the diagnostic accuracy of MARS MRI and ultrasound of the painful metal-on-metalhip arthroplasty. Acta Orthop. [Epub ahead of print]

  2. Hothi HS, Matthies AK, Berber R, Whittaker RK, Skinner JA, Hart AJ. (2014)The Reliability of a Scoring System for Corrosion and Fretting, and Its Relationship to Material Loss of Tapered, Modular Junctions of Retrieved Hip Implants. J Arthroplasty. pii: S0883-5403(13)00892-9.

  3. Matthies AK, Henckel J, Cro S, Suarez A, Noble PC, Skinner J, Hart AJ. (2014) Predicting wear and blood metal ion levels in metal-on-metal hip resurfacing. J Orthop Res. 32(1):167-74.

  4. Siddiqui IA, Sabah SA, Satchithananda K, Lim AK, Henckel J, Skinner JA, Hart AJ (2013). Cross-sectional imaging of the metal-on-metal hip prosthesis: The London ultrasound protocol. Clin Radiol. 68(8):e472-8

  5. Hart AJ, Muirhead-Allwood S, Porter M, Matthies A, Ilo K, Maggiore P, Underwood R, Cann P, Cobb J, Skinner JA. (2013). Which Factors Determine the Wear Rate of Large-Diameter Metal-on-Metal Hip Replacements?: Multivariate Analysis of Two Hundred and Seventy-six Components. J Bone Joint Surg Am 95(8):678-85

  6. Underwood RJ, Zografos A, Sayles R, Cann P, Hart AJ (2012). Risk Factors for Edge Loading in Metal-on-Metal Hip Arthroplasty. Mechanical Engineers, Part H: J Engineering Med226(3): 217-226

  7. Hart AJ, Satchithananda K, Liddle AD, Sabah SA, McRobbie D, Henckel J, Cobb JP, Skinner JA, Mitchell AW. (2012) Pseudotumors in Association with Well-Functioning Metal-on-Metal Hip Prostheses: A Case-Control Study Using Three-Dimensional Computed Tomography and Magnetic Resonance Imaging. J Bone Joint Surg Am 94(4):317-325

  8. Hart AJ, Skinner JA, Henckel J, Sampson B, Gordon F (2011) Insufficient acetabular version increases blood metal ion levels after metal-on-metal hip resurfacing. Clinical Orthopaedics and Related Research 469(9):2590-7. 

  9. Hart AJ, Quinn PD, Sampson B, Sandison A, Atkinson KD, Skinner JA, Powell JJ, Mosselmans JF. (2010). The chemical form of metallic debris in tissues surrounding metal-on-metal hips with unexplained failure. Acta Biomater. 6:4439-4446.

  10. Hart AJ, Sabah S, Henckel J, Lewis A, Cobb J, Sampson B, Mitchell A, Skinner JA. (2009) The painful metal-on-metal hip resurfacing. J Bone Joint Surg Br. 91(6):738-44. 

Professional Bodies/Awards/Other Sources of Funding

UCL Enterprise award 2014


Radiological Society of North America (2012)


American Academy of Orthopaedic Surgeons (2012)


Radiological Society of North America (2010)


US-UK Foreign Office Collaboration award (2010)


NHS Clinical Excellence Awards (2010)


Royal Society 350th Anniversary Exhibitor (2010)


The London Hip Meeting: Second Prize (2006)


WJ Little Medal, RNOH (2004)


RSM Presidents Prize: First Prize (2004)


British Trauma Society: First Prize (2003)


Other sources of funding include TSB, JRI Ltd, and Johnson & Johnson Ltd.

Conferences

British Hip Society (BHS) annual meetings, American Academy of Orthopaedic Surgeons (AAOS) annual meetings.


Alister Hart has been an invited speaker at the AAOS, Harvard Medical School, the British Orthopaedic Association, The German Orthopaedic Association

Rosetrees Partners

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